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Table 3 Phytochemical analysis of total alkaloid content, total phenolic content and radical-scavenging activity of leaf extracts of Apocynaceae species

From: Assessment of antiproliferative and antiplasmodial activities of five selected Apocynaceae species

Species MeOH crude extract aSequential extract
   HEX DCM DCM:MeOH MeOH
b Total alkaloid content (mg BE/g)     
Kopsia fruticosa 100 ± 4.2 63 ± 1.1 129 ± 4.0 99 ± 2.5 46 ± 1.6
Dyera costulata 58 ± 2.5 2.4 ± 0.6 11 ± 1.8 68 ± 2.7 41 ± 2.4
Alstonia angustiloba 23 ± 0.3 13 ± 2.3 27 ± 3.1 58 ± 1.2 27 ± 1.0
Calotropis gigantea 2.7 ± 0.3 3.7 ± 1.0 8.6 ± 1.2 9.6 ± 1.9 9.2 ± 2.7
Vallaris glabra 2.7 ± 0.4 4.4 ± 0.8 8.9 ± 0.6 9.2 ± 0.2 8.7 ± 2.2
b Total phenolic content (mg GAE/g)     
Dyera costulata 319 ± 5.5 21 ± 0.2 23 ± 0.1 354 ± 6.0 279 ± 3.0
Vallaris glabra 99 ± 3.8 15 ± 0.9 24 ± 0.5 134 ± 1.0 164 ± 13
Kopsia fruticosa 83 ± 1.1 39 ± 0.5 20 ± 0.5 129 ± 1.0 84 ± 1.0
Alstonia angustiloba 68 ± 2.0 17 ± 0.6 24 ± 0.6 96 ± 1.1 94 ± 1.1
Calotropis gigantea 28 ± 0.8 14 ± 0.6 44 ± 1.7 42 ± 0.8 33 ± 0.5
b Radical-scavenging activity (mg AA/g)     
Dyera costulata 377 ± 25 15 ± 0.3 9.3 ± 0.5 349 ± 21 278 ± 5.4
Vallaris glabra 84 ± 0.5 6.0 ± 0.3 8.4 ± 0.4 77 ± 2.2 119 ± 6.8
Kopsia fruticosa 63 ± 3.2 12 ± 1.4 7.5 ± 0.3 70 ± 2.0 48 ± 1.5
Alstonia angustiloba 29 ± 0.9 10 ± 0.2 5.7 ± 0.7 50 ± 1.2 46 ± 2.2
Calotropis gigantea 7.6 ± 0.4 5.6 ± 0.3 6.1 ± 0.4 8.0 ± 0.6 14 ± 1.3
  1. a HEX, hexane; DCM, dichloromethane; MeOH, methanol.
  2. b BE, boldine equivalent; GAE, gallic acid equivalent; AA, ascorbic acid. Values are in milligram per gram of extract.