Skip to main content

Table 2 Histomorphometric parameters of trabecular bone from metaphysis of tibiae evaluated by histochemical analysis.

From: Characterization of Salvia Miltiorrhiza ethanol extract as an anti-osteoporotic agent

Parameters

Sham

n = 7

OVX

n = 7

1SM

n = 7

3SM

n = 7

10SM

n = 7

30SM

n = 7

BV/TV (%)

55.44 ± 7.10

10.24 ± 3.68 *

11.51 ± 2.27

11.61 ± 2.27

15.19 ± 1.61

18.70 ± 1.38 #

Tb.Th (mcm)

35.14 ± 5.17

14.86 ± 5.54 *

15.72 ± 3.33

16.37 ± 3.03

21.32 ± 3.71

26.37 ± 2.49 #

Tb.N (1/mm)

15.87 ± 1.59

5.73 ± 2.03 *

6.06 ± 1.99

6.39 ± 2.00

8.88 ± 2.61

12.35 ± 2.67 #

Tb.Sp (mcm)

28.38 ± 5.80

199.70 ± 3.48 *

180.27 ± 3.46

176.26 ± 2.18

98.75 ± 7.21

81.67 ± 6.38 #

Oc.N/10 HPF

5 ± 1.41

17 ± 2.40 *

16 ± 2.39

17 ± 2.20

13 ± 2.26

10 ± 1.41 #

  1. Note: Results are presented as the means ± SD. *p < 0.001 vs. Sham group; # p < 0.05 vs. OVX group. BV/TV, bone volume fraction; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation; Oc.N, osteoclast number. Rat groups as defined above (N = 7/each group).