Skip to main content

Table 1 Trabecular microstructural properties of the right tibial metaphysis and cortical geometric properties evaluated ex vivo using micro-CT.

From: Characterization of Salvia Miltiorrhiza ethanol extract as an anti-osteoporotic agent

Parameters Sham
n = 10
OVX
n = 10
SM1
n = 7
SM3
n = 8
SM10
n = 10
SM30
n = 9
BV/TV (%) 30.06 ± 4.57 3.90 ± 1.61 * 4.56 ± 2.44 * 4.92 ± 1.84 * 6.22 ± 1.78 * 8.05 ± 3.32 *, #
Tb.Th (μm) 112.76 ± 7.95 96.51 ± 4.99 * 101.03 ± 6.58 * 100.06 ± 7.42 * 99.53 ± 5.92 * 107.03 ± 5.02 *, #
Tb.N (1/mm) 2.67 ± 0.40 0.40 ± 0.16 * 0.45 ± 0.23 * 0.50 ± 0.19 * 0.63 ± 0.19 * 0.93 ± 0.28 *, #
Tb.Sp (mm) 0.25 ± 0.08 1.05 ± 0.13 * 1.05 ± 0.26 * 1.03 ± 0.20 * 0.93 ± 0.21 * 0.71 ± 0.10 *, #
Conn.D (1/mm 3 ) 97.53 ± 12.90 8.95 ± 3.67 * 9.24 ± 4.90 * 10.59 ± 3.22 * 14.24 ± 6.62 * 19.37 ± 6.34 *, #
Tb.Pf (1/mm) 4.25 ± 2.29 20.35 ± 2.98 * 19.50 ± 2.26 * 18.98 ± 1.89 * 18.48 ± 2.62 * 15.79 ± 3.05 *, #
SMI (1) 1.46 ± 0.25 2.69 ± 0.10 * 2.64 ± 0.12 * 2.61 ± 0.14 * 2.59 ± 0.16 * 2.32 ± 0.26 *, #
Ct.Ar (mm 2 ) 5.38 ± 0.22 5.41 ± 0.45 5.98 ± 0.34 5.67 ± 0.43 5.58 ± 0.34 5.29 ± 0.31
Ct.Th (mm) 29.65 ± 0.13 29.63 ± 0.09 29.65 ± 0.07 29.54 ± 0.10 29.62 ± 0.06 29.66 ± 0.08
  1. Note: Results are presented as the means ± SD. *p < 0.001 vs. Sham group; # p < 0.05 vs. OVX group. BV/TV, bone volume fraction; Conn.D, connectivity density; SMI, structure model index; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation; Tb.Pf, Trabecular bone pattern factor; Ct.Ar, cortical area; Ct.Th, cortical thickness. Rat groups include sham-operated (Sham), OVX-control (OVX), and 1, 3, 10 and 30 mg/kg SM treated (1SM, 3SM, 10SM AND 30SM) ovariectomized groups for a total of 6 groups (N = 7~10/each group).