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Table 1 Trabecular microstructural properties of the right tibial metaphysis and cortical geometric properties evaluated ex vivo using micro-CT.

From: Characterization of Salvia Miltiorrhiza ethanol extract as an anti-osteoporotic agent

Parameters

Sham

n = 10

OVX

n = 10

SM1

n = 7

SM3

n = 8

SM10

n = 10

SM30

n = 9

BV/TV (%)

30.06 ± 4.57

3.90 ± 1.61 *

4.56 ± 2.44 *

4.92 ± 1.84 *

6.22 ± 1.78 *

8.05 ± 3.32 *, #

Tb.Th (μm)

112.76 ± 7.95

96.51 ± 4.99 *

101.03 ± 6.58 *

100.06 ± 7.42 *

99.53 ± 5.92 *

107.03 ± 5.02 *, #

Tb.N (1/mm)

2.67 ± 0.40

0.40 ± 0.16 *

0.45 ± 0.23 *

0.50 ± 0.19 *

0.63 ± 0.19 *

0.93 ± 0.28 *, #

Tb.Sp (mm)

0.25 ± 0.08

1.05 ± 0.13 *

1.05 ± 0.26 *

1.03 ± 0.20 *

0.93 ± 0.21 *

0.71 ± 0.10 *, #

Conn.D (1/mm 3 )

97.53 ± 12.90

8.95 ± 3.67 *

9.24 ± 4.90 *

10.59 ± 3.22 *

14.24 ± 6.62 *

19.37 ± 6.34 *, #

Tb.Pf (1/mm)

4.25 ± 2.29

20.35 ± 2.98 *

19.50 ± 2.26 *

18.98 ± 1.89 *

18.48 ± 2.62 *

15.79 ± 3.05 *, #

SMI (1)

1.46 ± 0.25

2.69 ± 0.10 *

2.64 ± 0.12 *

2.61 ± 0.14 *

2.59 ± 0.16 *

2.32 ± 0.26 *, #

Ct.Ar (mm 2 )

5.38 ± 0.22

5.41 ± 0.45

5.98 ± 0.34

5.67 ± 0.43

5.58 ± 0.34

5.29 ± 0.31

Ct.Th (mm)

29.65 ± 0.13

29.63 ± 0.09

29.65 ± 0.07

29.54 ± 0.10

29.62 ± 0.06

29.66 ± 0.08

  1. Note: Results are presented as the means ± SD. *p < 0.001 vs. Sham group; # p < 0.05 vs. OVX group. BV/TV, bone volume fraction; Conn.D, connectivity density; SMI, structure model index; Tb.Th, trabecular thickness; Tb.N, trabecular number; Tb.Sp, trabecular separation; Tb.Pf, Trabecular bone pattern factor; Ct.Ar, cortical area; Ct.Th, cortical thickness. Rat groups include sham-operated (Sham), OVX-control (OVX), and 1, 3, 10 and 30 mg/kg SM treated (1SM, 3SM, 10SM AND 30SM) ovariectomized groups for a total of 6 groups (N = 7~10/each group).