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Table 3 Extent of exposure (maximum 24 ampoules = 100%), percentage of subjects with local reactions and tolerability.

From: Safety and effects of two mistletoe preparations on production of Interleukin-6 and other immune parameters - a placebo controlled clinical trial in healthy subjects

  Iscucin®Populi Viscum Mali e planta tota Placebo
  (n = 30) (n = 21) (n = 20)
  0.0125% 0.25% 5% 1:1000 1:100 1:50    
  strength strength strength D3 D2 2%    
  F G H       
  Week Week Week Week Week Week Week Week Week
  1-4 5-8 9-12 1-4 5-8 9-12 1-4 5-8 9-12
Overall injected ampoules (%) 100.0 81.7 64.0 100.0 100.0 99.1 99.7 99.8 99.9
Local reactions % 17 93 93 0 19 19 0 0 0
Tolerability (%)   ** **    *    
Bad 0 28 21 0 0 0 0 0 0
Moderate 3 38 45 0 0 0 5 0 0
Good 21 34 34 5 14 29 0 0 0
Excellent 76 0 0 95 86 71 95 100 100
  1. *p < 0.05 versus Placebo, **p < 0.001 versus Placebo. Significant deviations are bold typed.