Biochemical assessment. Biochemical assessment of C57Bl/6 mice submitted to topical oral treatment with gel containing propolis (GP), compared to the group treated with the gel base (GS) or with saline (S). The serum concentrations of calcium (A); albumin (B); urea (C); cholesterol (D); triglycerides (E); and glucose (F) were determined. The results represent mean ± standard deviation of 6 animals/group. (*) p < 0.05 in relation to control and (#) p < 0.05 in relation to the other experimental group.