| |
Treatment groups
|
P(ANOVA)
|
|---|
|
Domain
|
Placebo
|
GTP
|
Placebo+TC
|
GTP+TC
|
Time
|
Time ± GTP
|
Time ± TC
|
Time ± GTP TC
|
|---|
|
Physical function
| | | | |
< 0.001
|
0.214
|
0.414
|
0.453
|
|
Baseline
|
77.7 ± 21.4
|
77.6 ± 21.7
|
78.4 ± 16.3
|
80.4 ± 19.1
| | | | |
|
12 week
|
72.9 ± 28.8
|
81.8 ± 21.2
|
80.9 ± 15.7
|
84.1 ± 15.6
| | | | |
|
24 week
|
65.9 ± 20.6
|
68.4 ± 20.4
|
68.1 ± 16.3
|
69.4 ± 16.4
| | | | |
|
Role-physical
| | | | |
0.136
|
0.477
|
0.578
|
0.466
|
|
Baseline
|
80.0 ± 34.7
|
78.4 ± 30.1
|
81.8 ± 33.2
|
84.6 ± 28.2
| | | | |
|
12 week
|
85.7 ± 28.6
|
83.8 ± 30.7
|
80.4 ± 36.4
|
86.8 ± 26.3
| | | | |
|
24 week
|
80.7 ± 31.6
|
89.2 ± 23.9
|
85.1 ± 28.5
|
89.7 ± 24.7
| | | | |
|
Bodily pain
| | | | |
0.703
|
0.679
|
0.947
|
0.791
|
|
Baseline
|
73.8 ± 19.2
|
73.2 ± 17.5
|
74.5 ± 17.3
|
76.6 ± 15.3
| | | | |
|
12 week
|
73.4 ± 19.3
|
74.2 ± 18.1
|
74.9 ± 16.5
|
76.2 ± 14.9
| | | | |
|
24 week
|
74.5 ± 18.4
|
73.9 ± 17.0
|
77.3 ± 16.4
|
76.1 ± 17.2
| | | | |
|
General health
| | | | |
0.168
|
0.676
|
0.917
|
0.114
|
|
Baseline
|
76.6 ± 16.5
|
72.9 ± 19.7
|
75.4 ± 16.2
|
76.4 ± 18.2
| | | | |
|
12 week
|
77.8 ± 13.6
|
75.1 ± 21.4
|
77.1 ± 16.4
|
77.3 ± 16.9
| | | | |
|
24 week
|
75.2 ± 16.0
|
76.0 ± 20.1
|
77.5 ± 16.2
|
76.5 ± 17.1
| | | | |
|
Vitality
| | | | |
0.064
|
0.305
|
0.576
|
0.160
|
|
Baseline
|
63.0 ± 20.7
|
58.0 ± 24.1
|
60.8 ± 23.0
|
64.7 ± 18.9
| | | | |
|
12 week
|
62.3 ± 22.4
|
59.5 ± 23.5
|
63.1 ± 21.7
|
67.9 ± 17.5
| | | | |
|
24 week
|
60.6 ± 19.7
|
64.2 ± 22.7
|
65.4 ± 22.7
|
68.7 ± 19.1
| | | | |
|
Social function
| | | | |
0.250
|
0.731
|
0.338
|
0.986
|
|
Baseline
|
89.3 ± 20.8
|
86.8 ± 20.2
|
85.1 ± 22.4
|
86.8 ± 16.6
| | | | |
|
12 week
|
88.6 ± 20.2
|
88.2 ± 20.8
|
87.5 ± 22.8
|
91.9 ± 14.7
| | | | |
|
24 week
|
85.7 ± 22.7
|
85.1 ± 22.4
|
86.1 ± 24.1
|
89.3 ± 18.2
| | | | |
|
Role-emotional
| | | | |
0.464
|
0.918
|
0.036
|
0.815
|
|
Baseline
|
87.6 ± 29.2
|
88.3 ± 25.1
|
77.5 ± 36.9
|
81.4 ± 30.9
| | | | |
|
12 week
|
89.5 ± 27.7
|
85.6 ± 31.0
|
81.1 ± 35.6
|
87.3 ± 30.7
| | | | |
|
24 week
|
85.7 ± 32.6
|
82.9 ± 33.0
|
88.3 ± 26.3
|
91.2 ± 20.6
| | | | |
|
Mental health
| | | | |
0.629
|
0.931
|
0.003
|
0.232
|
|
Baseline
|
80.2 ± 12.6
|
81.5 ± 11.5
|
77.4 ± 14.9
|
76.9 ± 15.7
| | | | |
|
12 week
|
80.8 ± 14.4
|
78.7 ± 14.3
|
78.3 ± 16.9
|
82.0 ± 10.8
| | | | |
|
24 week
|
78.6 ± 13.9
|
77.3 ± 17.1
|
81.3 ± 12.4
|
82.6 ± 10.0
| | | | |
- Data represent mean ± standard deviation (SD).
