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Figure 1 | BMC Complementary and Alternative Medicine

Figure 1

From: Effects of Hypericum Perforatum, in a rodent model of periodontitis

Figure 1

Inflammatory cells infiltration and edema were observed in gingivomucosal section from ligature-treated rats (b) when compared with gingivomucosal tissue section taken from controlateral side (a). Significantly less edema and inflammatory cell infiltration was observed in gingivomucosal sections from ligature-treated rats which had been treated with Hypericum (c). The total number of infiltrating leukocytes (e.g., neutrophil and mononuclear cells) in gingivomucosal tissue was assessed quantitatively by counting the number of polymorphonuclear cell in 20 high-power fields (d). Moreover Masson's trichrome stain was negative in gingivomucosal tissue sections taken from the contralateral side from vehicle when compared with gingivomucosal tissues sections of ligature-operated rats (e, f.). Hypericum treatment reduced the increase of collagen (Fig g) Figures are representative of at least 3 experiments performed on different experimental days. The tissue sections, orientated longitudinally from the teeth crown, were stained with trichrome stain. Data represent the mean ± S.E.M. for 20 counts obtained from the gingivomucosal tissue of each treatment group. * < P0.01 vs. non-ligated; °P < 0.01 vs. ligated.

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