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Table 3 Regression statistics, observed MIC (mg/mL) values and predicted MIC (mg/mL) values for all plant-extract and bacteria combinations with demonstrated inhibition in the disc diffusion assays.

From: Antibacterial activity of traditional medicinal plants used by Haudenosaunee peoples of New York State

Extracta

Bacteria

R 2

B (SE)b

MIC (obs)c

MIC (pred)d

Haudenosaunee medicinal plants

Am-FL

S. typhimurium

0.492

-0.112 (0.036)**

3.125

0.010

Am-FL

S. aureus

0.804

-0.667 (0.104)***

12.5e

19.1

Hp-FL

S. aureus

0.893

-0.818 (0.107)***

12.5e

36.0

Hp-LV

S. aureus

0.949

-1.196 (0.104)***

12.5e

23.6

Hp-ST

S. typhimurium

0.626

-0.108 (0.021)***

3.125

0.001

Ip-FL

S. aureus

0.791

-0.704 (0.114)***

12.5e

21.1

Ip-LV

E. coli

0.674

-0.169 (0.029)***

3.125

0.006

Ip-LV

S. typhimurium

0.853

-0.200 (0.026)***

3.125

0.023

Ip-LV

S. aureus

0.682

-0.425 (0.072)***

3.125

3.1

Ip-LV

S. lactis

0.859

-0.285 (0.030)***

3.125

0.1

Sc-LV

S. aureus

0.864

-0.640 (0.064)***

3.125

3.6

Plants with no known medicinal use by Haudenosaunee

Sv-LV

S. aureus

0.715

-0.221 (0.026)***

12.5e

10.1

Hm-ST

S. typhimurium

0.476

-0.134 (0.035)**

3.125

0.002

Rm-FL

E. coli

0.820

-0.236 (0.028)***

3.125

0.036

Rm-FL

S. typhimurium

0.696

-0.108 (0.021)***

3.125

0.053

Rm-LV

E. coli

0.714

-0.155 (0.024)***

3.125

0.004

  1. a A. millefolium (Am), H. matronalis (Hm), H. pilosella (Hp), I. pandurata (Ip), R. multiflora (Rm), S. virginica (Sv), S. canadensis (Sc); Flower (FL), Leaf (LV), Stem (ST).
  2. b Unstandardized regression coefficient and standard error. ** indicates P < 0.01; *** indicates P < 0.001. There were three replicates for each dilution series.
  3. c MIC (mg/mL) observed in serial dilution assay.
  4. d MIC (mg/mL) calculated utilizing 95% confidence limit of regression slope to conservatively predict the concentration at which the proportion of bacteria killed goes to zero.
  5. e Because the observed proportion of bacteria killed went to zero by the 6.25% dilution (6.25 mg/mL), the regression statistics were calculated using only the first four points of the dilution series.