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Table 3 Regression statistics, observed MIC (mg/mL) values and predicted MIC (mg/mL) values for all plant-extract and bacteria combinations with demonstrated inhibition in the disc diffusion assays.

From: Antibacterial activity of traditional medicinal plants used by Haudenosaunee peoples of New York State

Extracta Bacteria R 2 B (SE)b MIC (obs)c MIC (pred)d
Haudenosaunee medicinal plants
Am-FL S. typhimurium 0.492 -0.112 (0.036)** 3.125 0.010
Am-FL S. aureus 0.804 -0.667 (0.104)*** 12.5e 19.1
Hp-FL S. aureus 0.893 -0.818 (0.107)*** 12.5e 36.0
Hp-LV S. aureus 0.949 -1.196 (0.104)*** 12.5e 23.6
Hp-ST S. typhimurium 0.626 -0.108 (0.021)*** 3.125 0.001
Ip-FL S. aureus 0.791 -0.704 (0.114)*** 12.5e 21.1
Ip-LV E. coli 0.674 -0.169 (0.029)*** 3.125 0.006
Ip-LV S. typhimurium 0.853 -0.200 (0.026)*** 3.125 0.023
Ip-LV S. aureus 0.682 -0.425 (0.072)*** 3.125 3.1
Ip-LV S. lactis 0.859 -0.285 (0.030)*** 3.125 0.1
Sc-LV S. aureus 0.864 -0.640 (0.064)*** 3.125 3.6
Plants with no known medicinal use by Haudenosaunee
Sv-LV S. aureus 0.715 -0.221 (0.026)*** 12.5e 10.1
Hm-ST S. typhimurium 0.476 -0.134 (0.035)** 3.125 0.002
Rm-FL E. coli 0.820 -0.236 (0.028)*** 3.125 0.036
Rm-FL S. typhimurium 0.696 -0.108 (0.021)*** 3.125 0.053
Rm-LV E. coli 0.714 -0.155 (0.024)*** 3.125 0.004
  1. a A. millefolium (Am), H. matronalis (Hm), H. pilosella (Hp), I. pandurata (Ip), R. multiflora (Rm), S. virginica (Sv), S. canadensis (Sc); Flower (FL), Leaf (LV), Stem (ST).
  2. b Unstandardized regression coefficient and standard error. ** indicates P < 0.01; *** indicates P < 0.001. There were three replicates for each dilution series.
  3. c MIC (mg/mL) observed in serial dilution assay.
  4. d MIC (mg/mL) calculated utilizing 95% confidence limit of regression slope to conservatively predict the concentration at which the proportion of bacteria killed goes to zero.
  5. e Because the observed proportion of bacteria killed went to zero by the 6.25% dilution (6.25 mg/mL), the regression statistics were calculated using only the first four points of the dilution series.
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