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Table 3 Effects of SPP and SPE on Blood glucose, urea, creatinine and serum proteins of control and adjuvant induced arthritic rats

From: Evaluation of antiarthritic activity of Strychnos potatorum Linn seeds in Freund's adjuvant induced arthritic rat model

GROUPS Urea (mg/dl) Creatinine (mg/dl) Protein (g/dl) Albumin (g/dl) Globulin (g/dl) A/G ratio Cerruloplasmin (mg/dl) Fibrinogen (mg/dl)
Group I 22.64 ± 0.84 1.38 ± 0.06 6.62 ± 0.20 3.58 ± 0.06 2.30 ± 0.08 1.60 ± 0.10 19.65 ± 2.65 42.65 ± 2.28
Group II 30.54 ± 0.39 a* 2.38 ± 0.04 a* 4.28 ± 0.25 a* 2.36 ± 0.09 a* 2.86 ± 0.06 a* 0.79 ± 0.10 a* 52.74 ± 2.84 a* 162.45 ± 4.93 a*
Group III 23.15 ± 0.75 b* 1.67 ± 0.04 a#b* 5.32 ± 0.18 a*b* 3.02 ± 0.10 a*b* 2.54 ± 0.04 a*b* 1.15 ± 0.08 a*b* 22.12 ± 1.34 b* 88.04 ± 3.22 a*b*
Group IV 21.64 ± 0.83 b* 1.42 ± 0.03 b* 6.59 ± 0.19 b* 3.54 ± 0.12 b* 2.22 ± 0.06 b* 1.60 ± 0.11 b* 18.54 ± 1.24 b* 43.68 ± 4.14 b*
Group V 24.45 ± 0.64 b# 1.72 ± 0.08 a#b* 5.30 ± 0.20 a*b* 2.98 ± 0.08 a*b* 2.58 ± 0.08 a*b* 1.18 ± 0.07 a*b* 26.81 ± 2.46 a@b* 92.66 ± 5.64 a*b*
Group VI 25.88 ± 0.84 a@b# 1.79 ± 0.06 a*b* 5.24 ± 0.15 a*b* 2.89 ± 0.09 a*b* 2.62 ± 0.09 a*b* 1.12 ± 0.09 a*b* 26.24 ± 3.65 a@b* 98.53 ± 6.82 a*b*
Group VII 21.16 ± 1.28 b* 1.33 ± 1.06 b* 6.52 ± 0.19 b* 3.64 ± 0.07 b* 2.24 ± 0.04 b* 1.61 ± 0.04 b* 18.63 ± 2.94 b* 42.20 ± 7.87 b*
Group VIII 23.27 ± 0.84 b* 1.65 ± 0.06 a#b* 5.35 ± 0.16 a*b* 3.08 ± 0.06 a*b* 2.55 ± 0.06 a*b* 1.20 ± 0.08 a*b* 23.48 ± 2.45 b* 85.42 ± 8.60 a*b*
Group IX 24.84 ± 1.15 b# 1.68 ± 0.08 a#b* 5.30 ± 0.15 a*b* 2.97 ± 0.15 a*b* 2.58 ± 0.07 a*b* 1.18 ± 0.05 a*b* 24.35 ± 3.40 a@b* 93.60 ± 5.40 a*b*
  1. Values are Mean ± S.E.M, n = 6 animals in each group.
  2. Comparisons were made between: a- Group I vs II, III, IV, V, VI, VII, VIII, IX
  3. b- Group II vs III, IV, V, VI, VII, VIII, IX
  4. c- Group III vs V, VI, VIII, IX
  5. Symbols represent statistical significance: * - p < 0.001, # - p < 0.01, @ - p < 0.05
  6. in adjuvant induced arthritic rats.
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