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Table 3 Cytotoxicity of 5-FU and ethanolic extracts from 5 medicinal plants and one recipe with promising activity

From: Cytotoxic activity of Thai medicinal plants against human cholangiocarcinoma, laryngeal and hepatocarcinoma cells in vitro

Plants Cell line
  CL-6 HepG2 Hep-2 HRE
  IC50 SI IC50 SI IC50 SI IC50
Atractylodes lancea 24.09 ± 3.40 8.6 76.68 ± 15.94 2.7 29.35 ± 8.66 7.1 207.59 ± 7.97
Kaempferia galangal (leaf) 37.36 ± 3.98 2.9 115.47 ± 26.23 0.9 18.99 ± 10.33 5.7 119.20 ± 14.91
Zingiber officinal 34.26 ± 7.65 3.5 9.67 ± 3.91 12.6 32.40 ± 6.70 3.8 121.50 ± 5.20
Piper chaba 40.74 ± 5.30 4.5 68.09 ± 22.58 2.7 18.93 ± 5.03 9.8 119.14 ± 9.94
Pra-Sa-Prao-Yhai recipe 44.12 ± 11.58 5.9 125.07 ± 3.08 2.11 20.99 ± 2.68 12.5 263.51 ± 29.06
Mesua ferrea 48.23 ± 5.84 2.5 86.47 ± 4.38 1.4 19.22 ± 5.31 6.3 121.77 ± 29.08
5-FU (μM) 757.00 ± 77.16 2.0 633.08 ± 284.25 2.4 141.49 ± 17.14 10.8 1542.20 ± 1529.11
  1. Data are presented otherwise specified as mean ± SD of IC50 (μg/ml) from 3 independent experiments, triplicate for each.