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Table 2 GST Specific Activity against 4-Nitroquinoline 1-oxide (Specific activity expressed as units/mg of protein)

From: In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids

Samples

Stomach

Intestine

Liver

Lung

Control

0.519 ± 0.06

0.322 ± 0.06

1.720 ± 0.34

0.414 ± 0.19

Mixture

0.755 ± 0.04**

0.624 ± 0.18**

1.765 ± 0.40

0.426 ± 0.04

Nomilin

0.927 ± 0.12**

0.905 ± 0.13**

2.045 ± 0.25

0.351 ± 0.08

Deacetyl nomilin

0.594 ± 0.12

0.558 ± 0.17 **

1.551 ± 0.30

0.431 ± 0.04

Isoobacunoic Acid

0.592 ± 0.02

0.604 ± 0.57

1.179 ± 0.05

0.374 ± 0.02

  1. Results are means ± SD (n = 4)
  2. * indicate statistically significant (p < 0.05) reduction of QR activity was observed.
  3. ** indicate statistically significant (p < 0.01) induction of QR activity was observed.