Figure 6

Comparison of the cytotoxic effect of SC/D-F9 with docetaxel, doxorubicin and paclitaxel on prostate cancer cells. DU-145 and PC-3 cells were treated with 7.2 and 7.4 μg/ml SC/D-F9, respectively, 5 and 20 nM docetaxel (Dc5, Dc20), 10 and 100 nM doxorubicin (Dx10, Dx100) and 5 and 50 nM paclitaxel (P5, P50) and, for 24 and 48 hr. The control cultures contained 0.1% DMSO. The percentages of cell death induced were determined using the LDH release assay and each data represents the mean ± SD from three independent experiments. Statistical analysis was determined using the Student T test with * p < 0.05; ** p < 0.01; *** p < 0.001, compared to control.