Fig. 6

Fer-1 reduces RPM-induced hepatotoxicity by regulating GPX4 expression and ROS accumulation. A: GPX4 protein level in L02 cells treated with Fer-1 and RPM (n = 3). ^**P<0.01, vs. the CON group; ^##P < 0.01, vs. the RPM group; ^&&P<0.01, vs. the RPM group. B: ROS accumulation in L02 cells treated with RPM and Fer-1 (n = 3). ^**P<0.01, vs. the CON group; ^##P < 0.01, vs. the RPM group; ^&&P<0.01, vs. the RPM group