Fig. 5
Effect of AZC on the expression of ERK1/2 in the hydrogen peroxide induced SH-SY5Y cell toxicity was detected by Western blotting. (a) Representative Western blot showing the levels of total p-ERK1/2/ERK1/2. (b) Relative density of total p-ERK1/2/ERK1/2. Data are presented as mean ± SEM. aap < 0.01; compared to naïve control, *, **p < 0.05 and 0.01, respectively; compared to SH-SY5Y cells treated with hydrogen peroxide, and which had received the vehicle. ERK1/2: extracellular signal-related kinases 1 and 2; H2O2: hydrogen peroxide at dose of 200 µM; AZC low dose and AZC high dose: the anthocyanin-rich extract derived from Zea mays L. var. ceratina at doses of 62.5 and 125 µg/mL, respectively